I like a lot of the story ideas already presented. And I'm on record saying I find this an unending quagmire and my best option would be a reset. But I really think that would be more of a disservice to the fans, so, I'd hope to see something along these lines....
STRUCTURE & TIMING. A forward flow. Act 1 & 2 daytime, Act 3 noon/lunch, Act 4 afternoon, 5, 6 evening (I think I counted those acts right). Cliffhangers get resolved in the opener the next day. Conversations convey information from one person to another. The next day, new conversations take place between the same people ("I thought about what you said yesterday,") OR new people are in the conversation ("I was talking to Daniel yesterday, he thinks...but I think...") and information continues to be conveyed anew.
People start using temporal terms, like "Last night I spoke to so-and-so." With a few exceptions, 1 day = 1 show. This would also allow us to see people at work, and at play. (This was how I structured my fan fiction "episodes".) I'll admit this structure would be harder to summarise, but if done well, keeps the story moving and keeps folks from falling out of the loop too quickly if they miss a few shows.
CHARACTERISATION. Consistent. How does this character react to this situation? How can I create the drama of a failed business, without forgetting what I already know about a character's business acumen? If I "know" this character after watching him for years, will I believe his reaction to this turn/change/secret?
Diverse. I'd really like to see a character who doesn't go to church when everyone else does, or one who goes to a different church. I'd like to see people pray (or not) based on their characterisation and not what the plot demands at the moment. I'd like to see little disagreements based on big issues, but not just as plot points. As character traits. They can evolve, but not change suddenly.
Intelligent. I want to see characters I can root for, who make the plot move forward by putting 2+2 together. Characters who stand up for themselves, who realise that most things in this life are temporary, and who move forward from bad situations.
FAMILY/CASTING. I want to see Bradys, Hortons, Reeds, Blacks, DiMeras, Kiriakii, Johnsons, Deveraux, Ramirez, Donovans, Hernandez, Lombards. Cycle in and out a little more. Maybe April is the month of Hortons, Reeds, and Ramirez; then in May/June, the Johnsons are moving the story. (This is the least realistic of all, as having actors available is a big issue. But this is my dream list, so I'll include it.)